Billions of dollars in illicit drug proceeds flows through the U.S. financial system through elaborate money laundering schemes. This issue of the Eye on Fraud discusses the rise of opioids and common trafficking methods and schemes. Through the use of recent and relevant cases studies, this article will demonstrate how perpetrators are using and abusing the U.S. financial system. In addition, it outlines key red flags and practice tips that can be implemented by forensic accountants and investigators that perform